Synthesis, Characterization and Anti-Microbial Activity of Novel Pyramidine Derivatives

Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 3 of the six-member ring. Three nucleobases found in nucleic acids, cytosine (C), thymine (T), uracil (U), are pyrimidine derivatives. A has many properties common with as number ring increases pi electrons become less energetic electrophilic substitution gets more difficult while nucleophilic easier. Chalcones react aminoguanidine give intermediate compounds which on further reacts substituted ketones Pyramidine total 6 were synthesized from one scheme they recrystallized by appropriate solvents. They identified characterized various spectral methods. In present study, all tested for anti bacterial activity anti-fungal activity. shown significant when compared standard drug Streptomycin Miconazole respectively. Keywords: Pyramidines, Characterization, Streptomycin, Miconazole, Anti-microbial